Dog & Cat HospitalCalabasas

Patient Education

Cancer, Masses & Lumps

A cancer diagnosis is frightening, but modern veterinary oncology offers more options than ever — and early evaluation is the single most important step.

Cancer is the leading cause of disease-related death in dogs and the second leading cause in cats. It encompasses an enormous variety of conditions — from easily removed skin lumps to aggressive tumors affecting internal organs — and no two cancers behave the same way. What unifies them is abnormal, uncontrolled cell growth that invades surrounding tissue and, in malignant cases, may spread (metastasize) to distant sites. The most important truth about veterinary cancer: a lump is not a diagnosis. Only sampling — fine-needle aspiration or biopsy — tells us what a mass actually is, and that answer determines everything about prognosis and treatment. At Dog & Cat Hospital Calabasas, our team evaluates new masses with in-house cytology, CT imaging, and excisional biopsy, and we coordinate with veterinary oncology specialists when chemotherapy or advanced radiation therapy is appropriate.

Signs & Symptoms

Signs of cancer are highly variable depending on the tumor type and location. Common warning signs that deserve prompt evaluation include:

  • A new lump, bump, or swelling anywhere on or under the skin — especially one that changes size over weeks
  • A wound or sore that fails to heal
  • Unexplained weight loss or muscle wasting
  • Loss of appetite and lethargy persisting more than a day or two
  • Abnormal bleeding or discharge from any body opening
  • Difficulty breathing, swallowing, or eating
  • Lameness or swelling over a bone without a clear injury (bone tumors can mimic arthritis)
  • A distended or painful abdomen
  • Straining to urinate or defecate
  • Changes in behavior, vision, or coordination (brain tumors)

Many of these signs are caused by non-cancerous conditions too — which is exactly why a thorough work-up matters more than guessing based on appearance alone.

Causes & Risk Factors

Cancer develops from a combination of genetic predisposition, environmental exposures, and aging-related DNA damage. Risk factors include:

  • Age — the risk of most cancers rises sharply after age seven in dogs and nine in cats
  • Breed — certain dog breeds carry dramatically elevated cancer risks: Golden Retrievers (hemangiosarcoma, lymphoma, mast cell), Boxers (mast cell, lymphoma, brain tumors), Bernese Mountain Dogs (histiocytic sarcoma), Rottweilers (osteosarcoma)
  • Reproductive status — intact female dogs have a significantly higher risk of mammary tumors, and intact male dogs have higher rates of testicular and prostate cancers
  • Chronic inflammation — long-standing skin infections, sun damage on pale skin, or chronic wounds can predispose to certain tumor types
  • Secondhand smoke and certain environmental chemical exposures have been associated with nasal and bladder cancers in dogs
  • Feline leukemia virus (FeLV) — a major risk factor for lymphoma and other cancers in unvaccinated cats with outdoor exposure

Found a new lump on your dog or cat?

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How We Diagnose It

The goal of diagnostic work-up is to answer three questions: What is it? How aggressive is it? Has it spread? Our toolkit includes:

  • Fine-needle aspiration (FNA) cytology — a quick, low-cost, minimally invasive first step; a small needle samples cells from the mass, which are examined under a microscope; gives a presumptive answer in many cases on the same day
  • Excisional or incisional biopsy — removes tissue for formal pathology; provides definitive diagnosis, grade, and margin assessment; performed by Dr. Alan Schulman
  • Complete blood panel and urinalysis — screens for systemic effects of cancer (anemia, abnormal calcium, clotting disorders)
  • Chest X-rays — standard screening for lung metastasis before any surgical procedure
  • Abdominal ultrasound — evaluates internal organ involvement and lymph node size
  • CT scan — our on-site CT provides detailed imaging of chest, abdomen, and bones for staging complex cases without an off-site referral

Treatment Options

Cancer treatment is not one-size-fits-all; a plan is built around tumor type, stage, the individual patient's health, and the owner's goals:

  • Surgery — the primary treatment for most solid tumors; complete surgical removal (wide margins) is curative for many localized cancers; Dr. Schulman's oncologic surgery expertise guides margin planning and reconstruction when complex anatomy is involved
  • Chemotherapy — used for systemic cancers (lymphoma, leukemia), high-grade tumors at risk for metastasis, or as adjuvant therapy after surgery; protocols vary from weekly injectable to monthly oral regimens; most pets tolerate veterinary chemotherapy with far fewer side effects than humans experience
  • Palliative and supportive care — pain management, appetite support, and anti-nausea therapy to maintain quality of life when cure is not the goal; can be highly effective for months
  • Watchful waiting — for some slow-growing, low-risk tumors (certain lipomas, small benign skin masses in senior patients) monitoring with periodic FNA is a reasonable approach

Specialist oncology referral is coordinated when radiation therapy or advanced protocols are indicated — we prepare the full diagnostic package so a referral visit is immediately productive.

When to See Our Team in Calabasas

Any new lump that has appeared or grown in the past four to six weeks deserves a same-week appointment for aspiration. Waiting and watching without sampling is rarely the right answer — even a benign result gives peace of mind, and a malignant result caught early means more options. Pets showing systemic signs — weight loss, persistent fatigue, difficulty breathing — need evaluation promptly. Our Calabasas team can aspirate, image, and stage many cancers without sending you elsewhere first, saving time when it matters most. Book an appointment today.

Frequently Asked Questions

1How common is cancer in dogs?
Cancer is the leading cause of death in dogs over the age of two, affecting roughly one in four dogs at some point in their lives. Some breeds — particularly Golden Retrievers and Bernese Mountain Dogs — have very high lifetime cancer rates.
2What does a cancerous lump look like on a dog or cat?
There is no reliable way to tell whether a lump is cancerous from appearance alone. Smooth, soft lumps can be malignant; rough or firm ones can be benign. The only way to know is needle aspiration or biopsy — never judge a lump by how it looks or feels.
3Can cancer in pets be cured?
Some cancers are curable with surgery or surgery plus chemotherapy, particularly when caught early and completely removed. Others are managed as chronic diseases with the goal of maintaining quality of life. The prognosis varies enormously by cancer type, grade, and how far it has spread at diagnosis.
4Is chemotherapy very hard on dogs and cats?
Veterinary chemotherapy protocols are designed with quality of life as a primary goal. Most pets tolerate treatment well, with only mild and temporary side effects in the majority of cases. The drugs, doses, and intervals are chosen to maximize tumor effect while minimizing how sick the pet feels.
5What happens if a tumor is not removed or treated?
Outcomes vary by tumor type. A benign lipoma may grow slowly for years without harm. A malignant mast cell tumor may spread rapidly. An untreated lymphoma shortens life to weeks without treatment. Getting an accurate diagnosis early is the only way to know what you're actually dealing with.
6How much does cancer treatment cost for dogs and cats?
Costs range widely based on tumor type, treatment chosen, and the individual patient. A simple surgical removal with biopsy is very different in scope from multi-drug chemotherapy. We provide detailed estimates at the diagnostic consultation so owners can make informed decisions.
7Should I get my pet's lump tested even if it doesn't seem to bother them?
Yes — most tumors are not painful in their early stages. Pets rarely show signs until a tumor is large or has started to affect organ function. Testing an apparently pain-free lump while it is still small is almost always the best strategy.
8Does spaying or neutering prevent cancer in pets?
Spaying female dogs before their first heat dramatically reduces the risk of mammary tumors — one of the most common cancers in dogs. It also prevents ovarian and uterine cancers. Neutering males eliminates testicular cancer. The relationship between reproductive status and some other cancers (lymphoma, osteosarcoma) is more complex and breed-specific.

Found a new lump on your dog or cat?

Don't wait and wonder — a quick needle aspiration gives an answer the same day in most cases. Early diagnosis means more treatment options.

Book an Appointment